PredictiveandComputationalToxicology
S-2
ClinicalToxicology
YT-1
InvitedSpeakers
VT-1
VeterinaryToxicologyForuminvitedspeakers
RT-1
RespiratoryToxicologyForumInvitedSpeakers
15:30-17:30
S-3
ReproductiveandDevelopmentalToxicology
S-4
OrganChipsandOrganoidsinToxicology
YT-2:
MechanisticToxicology(1)
VT-2
ProfessionalCommitteeGeneralElection
RT-2
ToxicologyofAirPollutants
Friday,22October
08:00-10:00
S-5
COVID-19VaccinesandTherapeutics:fromIndustrytoRegulatory
Perspectives
S-6
NonclinicalSafetyTestingStrategyofNovelTherapies
YT-3
MechanisticToxicology(2)
VT-3
ClinicalVeterinaryToxicology
RT-3ZT-1
MolecularMechanismofZhejiangSocietyofRespiratoryToxicologyToxicologyForumInvited
Speakers
10:10-12:00
S-7
ICHM7PrincipalsandNitrosamines
S-8
AlternativeToxicityTesting
YT-4
NewTechnologyandModelofToxicology
VT-4
BasicVeterinaryToxicology
RT-4
InhalationToxicityandSafety
ZT-2
MOOChelpstoreformthe
modeoftoxicologyteaching
13:30-15:20
S-9
ChemicalStewardship
throughSustainabilityLenses
S-10
Toxicology&EpigeneticsBiomarkersandCancer
YT-5
AppliedToxicology
VT-5
VeterinaryToxicologyYoungScholarForum
RTRA
RegulatoryToxicologyandRiskAssessment
ZT-3
ToxicologyScholarForum
S-11
Nanotoxicology
S-12
GutMicrobiotaandToxicEffectsofPollutants
YT-6
Exhibition&PosterViewing/Discussion
VT-6
VT-6:SummaryofVeterinaryToxicology
RTRAZT-4
RegulatoryToxicologyandYoungScholarForumandRiskAssessmentRoundTableDiscussion
Saturday,23October
08:30-11:00
10:40-11:15
AwardCeremonyofCST/AssemblyMeetingofASIATOXCouncil
11:15-11:35
ClosingCeremony
OpeningCeremony/PlenaryLecture
OpeningCeremonyChair:ChunyingChen
PlenaryLecture(PL)
Chairs:YuepuPu,JunKanno
09:30-10:00
PL-1ToxicologyinAsia-past,present,andfuture
TetsuoSatoh(ATS,EDJSOT,EmeritusProf.,ChibaUniversity)
10:00-10:30
PL-2TheprogressofclinicaltrialsofCOVID-19vaccine
FengcaiZhu(JiangsuProvincialCenterforDiseaseControlandPrevention)
10:30-10:40
CoffeeBreak
10:40-11:10
PL-3Datadrivencandidate-drugsafetyassessmentinlargepharma-challengesandopportunities
LalitKumarVerma(DirectorofNon-ClinicalSafetyDataScienceatJanssen)
11:10-11:40
PL-4Evolutionoffoodriskassessment:frompublicpolicymakingtopersonalhealthychoice
HoonjeongKwon(SeoulNationalUniversity)
12:00-13:30
LunchBreak
BaoshengHall,宝盛厅(On-site/Virtual)
PlenaryLecture/ClosingCeremony
Chairs:HuaLi,SalmaanInayat-Hussain
08:30-9:00
PL-5Humanorgans-on-a-chip:anewtrendoftoxicitytestingalternatives
ZhongzeGu(SchoolofBiologicalScienceandMedicalEngineering,SoutheastUniversity)
PL-6Adaptiveresponseandprotectionagainstelectrophilicstress
YoshitoKumagai(UniversityofTsukuba)
PL-7CertificationandrecognitionoftoxicologistsinChina
LijieFu(ChineseSocietyofToxicology）
10:00-10:10
10:10-10:40
PL-8Advancedglycationendproductsanddiabeticretinopathy:Thepossiblemolecularmechanismsinvolvedinangiogenesiseffects
Meei-LingSheu(NationalChungHsingUniversity)
AwardceremonyofCST
Chair:ChaoLiu
AssemblyMeetingofASIATOXCouncil
Chair:LijieFu
Chair:ChunyingChen
Hall1/宝盛厅1(On-site/Virtual)
S-1:PredictiveandComputationalToxicologyChairs:TakashiYamada,JingwenChen
13:30-13:50
Deeplearningonmolecularstructureforestrogenreceptoragonismofchemicals
AiqianZhang(ResearchCenterforEco-EnvironmentalSciences,ChineseAcademyofSciences)
13:50-14:10
Developmentandimprovementofinsilicoapproachesforacceleratingregulatorychemicalriskassessment
TakashiYamada(NationalInstituteofHealthSciencesinJapan)
14:10-14:30
Machinelearningasapowerfultooltoanalyzecomplicatedbiologicalresponses
XiangangHu(CollegeofEnvironmentalScienceandEngineering,NankaiUniversity)
14:30-14:50
Read-acrossapproachforchemicalhazardassessment
YingWang(Procter&Gamble,China)andSogaKwon(Procter&Gamble,Singapore)
14:50-15:10
Couldsuperoxideradicalbeimplementedindecontaminationprocesses
RuiyangXiao(InstituteofEnvironmentalEngineering,SchoolofMetallurgyandEnvironment,CentralSouthUniversity)
15:10-15:30
S-3:ReproductiveandDevelopmentalToxicologyChairs:TsuyoshiNakanishi,LiZhou,YingJiang
15:30-15:50
Molecularandcellularmechanismsofandrogen-drivensexdifferentiationinmurineexternalgenitalia:Towardtoinsightsintothereproductiveorgantoxicology.
KentaroSuzuki(WakayamaMedicalUniversity)
15:50-16:10
Assessmentofdevelopmentaltoxicitycausedbyorganophosphatetriestersandtheirmetabolitesusingzebrafish
AkiraKubota(ObihiroUniversityofAgricultureandVeterinaryMedicine)
16:10-16:30
Effectsofglufosinate-ammoniumonmalereproductivehealth:Focusonepigenomeandtranscriptomeinmousesperm
YankaiXia(SchoolofPublicHealth,NanjingMedicalUniversity)
16:30-16:50
ExposuretoBPSexertscytotoxiceffectonmouseLeydigcells:involvementofmitochondrialdysfunctionanddefectivemitophagy
DaleiZhang(SchoolofBasicMedicalSciences,NanchangUniversity)
16:50-17:10
AweightofevidenceassessmentofdevelopmentalandreproductivetoxicityofdiisononylphthalateunderGHS
HanjunZou(ExxonMobil(China)InvestmentCo.,Ltd.)
S-5:COVID-19VaccinesandTherapeutics:fromIndustrytoRegulatoryPerspectivesChairs:NanMei,YongbinZhang
08:00-08:10
TheintroductionofSOTandAACT
YongbinZhang(FDA/CDER,USA)
08:10-08:40
Overviewofnon-clinicalsafetyassessmentforantiviraldrugsandvaccinesdevelopment
HananGhantous(FDA/CDER,USA)
08:40-09:10
Non-clinicalsafetyassessmentforpreventativevaccinesdevelopment
NabilAl-Humadi(FDA/CBER,USA)
09:10-09:35
RapiddevelopmentofREGN-COV2,ananti-spikeantibodycocktailfortreatmentandpreventionofCOVID-19
MattY.Liu(RegeneronPharmaceuticals,USA)
09:35-10:10
DevelopmentofmRNACOVID-19vaccineBNT162b2inChina
AiminHui(FosunPharma,China)
10:10-10:20
S-7:ICHM7PrincipalsandNitrosaminesChair:JoanneBirkebak
10:10-10:15
Openingremarks
JoanneBirkebak
10:15-10:40
Introduction-TBD
AndreasHartmann(Novartis)
10:40-11:05
AssessmentofnitrosaminesinAmesassay
AndreasCzich(Sanofi,thePreclinicalSafetyOperationalCenterinFrankfurt)
11:05-11:30
Derivationofacceptableintakesfornitrosamines:structuralgroupsandcompound-specificlimits
MichelleKenyon(PfizerResearchandDevelopmentinGroton)
11:30-11:50
Considerationsforlessthanlifetimeapproach
AlejandraTrejo-Martin(GileadSciences)
S-9:ChemicalStewardshipthroughSustainabilityLensesChair:SalmaanInayat-Hussain
13:30-13:40
Chemicalstewardshipthroughsustainabilitylenses
SalmaanInayat-Hussain(PETRONAS,Malaysia)
13:40-14:05
Corporatesustainabilityassessment–ratingthroughtheESGlens
AndersAlmtoft(S&PGlobal,Switzerland)
14:05-14:30
Keyconsiderationsonselectionofsaferchemicalalternatives
EevaLeinala(OECD,France)
14:30-14:55
Sustainablemetricsforgreentoxicology
AlexandraMaertens(JohnsHopkinUniversity,USA)
14:55-15:20
Managementofreprotoxicantsthroughthelensofsustainability
MasaoFukumura(PETRONAS,Malaysia)
15:20-15:30
S-11:Nanotoxicology
Chairs:ChunyingChen,PuchunKe
AllroadsleadtoRome,diversemechanismsofnanomaterial-inducedcelldeath
TianXia(UniversityofCalifornia,LosAngeles,Medicine)
Understandingtheaggregationandtoxicityofamyloidproteins
PuchunKe(MonashInstituteofPharmaceuticalSciences,MonashUniversity)
Useofnano/bioprinciplestodesignsafernanomedicine
HuanMeng(NationalCenterforNanoscienceandTechnology)
Thebiologicaleffectandsafetyevaluationmethodoforalingestionofnanoparticles
YanLi(UniversityofShanghaiforScienceandTechnology)
Cell-nanoparticleinteractionsandtheirimplicationsfornanotoxicity
AngelaIvask(InstituteofMolecularandCellBiology,TartuUniversity,Estonia)
Hall2/宝盛厅2(On-site/Virtual)
S-2:ClinicalToxicology
Chairs:Chen-ChangYang,WeiSong
Toxicoepidemiologicstudiesusingpoisoncontrolcenterdataandotherdatabases
SahaphumeSrisuma(DivisionofToxicology&ClinicalPharmacology,DepartmentofInternaMedicine,RamathibodiHospital,Bangkok,Thailand)
ChristopherHoyte(RockyMountainPoisonCenter,ToxicologyClinic,UniversityofColoradoHospital)
Prosandconsofusingclaimsdatainepidemiologicstudiesofacutepoisoning:COpoisoningasanexample.
Chen-ChangYang(InstituteofEnvironmental&OccupationalHealthSciences,SchoolofMedicine,NationalYangMingChiaoTungUniversity)
EpidemiologicalstudyonpoisoninginmainlandChina
ChengyeSun(ChineseCenterforDiseaseControlandPrevention)
Pancreaticinjuryafterparaquatingestion
YiLi(PekingUnionMedicalCollegeHospital)
S-4:OrganChipsandOrganoidsinToxicologyChairs:JosJoore,LijieFu
15:30-15:40
Sessionintroduction
LijieFu(CST)andJosJoore(MIMETAS)
15:40-16:00
Humantissuemodelsfordevelopingsafeandeffectivetherapies
SebastiaanTrietsch(MIMETAS)
16:00-16:30
Organ-chipsandorganoidsinpreclinicalsafety
MichaelBscheider(RocheInnovationCenterBasel)
16:30-17:00
Mechanisticinvestigationofdrug-inducedorgantoxicityutilizinghumantissuemodels
MasatoOhbuchi(AstellasPharmaInc.)
17:00-17:30
3Dbioprinting:fromorganmodelstotissuesrepair
YongHe(MechanicalEngineering,ZhejiangUniversity)
S-6:NonclinicalSafetyTestingStrategyofNovelTherapiesChair:JackXie
08:00-08:30
Genetherapyandpotentialsafetyconsiderations:Focusongenomeintegration
JingYuan(Pfizer)
08:30-09:00
NonclinicalSafetyEvaluationofT-cellImmunotherapies
TimothyMacLachlan(NovartisInstitutesforBiomedicalResearch)
NonclinicaldevelopmentandFIHenablingofbispecificantibodies
RyanMeng(JanssenChinaR&D)
Safetyassessmentstrategiesandkeyconsiderationsforoligonucleotides
TianyiJiang(RocheInnovationCenterShanghai)
S-8:AlternativeToxicityTesting
Chairs:ShuangqingPeng,HajimeKojima
10:10-10:30
AlternativemethodsfordevelopmentalandreproductivetoxicitytestingregardingICHS5(R3)
HajimeKojima(CenterforBiologicalsafetyandResearch,NationalInstituteofHealthSciences,Japan)
10:30-10:50
Generationofhierarchicalvascularizedinvitrotissuesbasedonassembloidprintingtechnology
YuanPang(DepartmentofMechanicalEngineering,TsinghuaUniversity)
10:50-11:10
SkinEthicTMHCETime-to-Toxicitytestingmethodforsubcategorizationofeyeirritation
11:10-11:30
Animalalternativesinneurotoxicologicalresearch
SheikhRaisuddin(DepartmentofMedicalElementology&Toxicology;HamdardUniversity,NewDelhi,India)
HaoKou(ZhongnanHospitalofWuhanUniversity)
11:50-12:10
Integrationofinvitrotoxicitytestingandinsilicomodelinginchemicalriskassessment
JiabinGuo(CentersforDiseaseControlandPrevention)
S-10:Toxicology&EpigeneticsBiomarkersandCancerChairs:JunKanno,YiguoJiang
Histonemodification,DNAmethylation,andmRNAexpressionanalysisofmurineliverrepeatedlyexposuretoachemical
JunKanno(DivisionofCellularandMolecularToxicology,CenterforBiologicalSafetyResearch,NIHS,Kawasaki,Kanagawa,Japan)
Roleofnon-codingRNAsinmalignant16HBEcellstransformedbyanti-benzopyrene-trans-7,8-dihydrodiol-9,10-epoxide
YunZhou(GuangzhouMedicalUniversity)
Valueoftwinandfamilystudiesinenvironmentalepigeneticresearch
ShuaiLi(TheUniversityofMelbourne)
NovelhepatotoxicitybiomarkersofexosomalmiRNAsacutelyinducedbyCCl4
RyuichiOno(NationalInstituteofHealthScience)
Epigenotoxicityandcancerandrelateddiseases:Futureperspectives
MohammadAbdollahi(TehranUniversityofMedicalSciences)
Toxicologyandepigeneticsbiomarkersforarsenic-inducedcancer:ApopulationbasedstudyfromWestBengal,India
PrithaBhattacharjee(UniversityofCalcutta)
S-12:GutMicrobiotaandToxicEffectsofPollutantsChairs:RuixueHuang,Cheng-YuanKao
Radiationandgutmicrobiota
RuixueHuang(CentralSouthUniversity)
CancerriskofspaceradiationenvironmentanditsregulationbylncRNAs
GuangmingZhou(SoochowUniversity)
PAHsandcancer
ZhihuiFeng(ShandongUniversity)
Toxicologicalstudybasedonmetabolicevaluationtechnology
ZhongzeFang(TianjinMedicalUniversity)
Gutmicrobiota,metabolismandobesity
Cheng-YuanKao(NationalHealthResearchInstitutes)
Hall3/宝盛厅3(On-site，线下)
YouthForumofScience&Technology，中青年科技论坛
YT-1:InvitedSpeakers邀请报告
Chairs主席:ZuyueSun/孙祖越，QingshanWang/王青山
13:30-13:55
Evaluatingconsumerexposuretodisinfectingchemicalsagainstcoronavirusdisease2019(COVID-19)andassociatedhealthrisks
DingshengL/李丁生(UniversityofNevadaReno美国内达华大学)
13:55-14:20
Themechanismandroleofmelatoninintherapidrecoveryofplateletspostradiationexposure褪黑激素促进辐射暴露后血小板快速恢复的机制和作用
ShileiChen/陈石磊(ThirdMilitaryMedicalUniversity,第三军医大学)
14:20-14:45
Antitumoreffectandbiosafetyevaluationofmetalnanomaterials金属纳米材料的抗肿瘤作用及生物安全性评价
JingLiu/刘晶(NorthwestUniversity,西北大学)
14:45-15:10
Epigeneticmechanismofcellmigrationandinvasionpromotedbyexposuretoendosulfaninhumanprostatecancercells
硫丹暴露促进前列腺癌细胞迁移和侵袭的表观遗传机制研究
DanXu/徐丹（DalianMaritimeUniversity,大连海事大学）
TeaBreak
YT-2:MechanisticToxicology(1)机制毒理学-1
Chairs主席:QianBian/卞倩，HuaWang/王华
TheroleandunderlyingmechanismsofNOX2inenvironmentaltoxins-induceddopaminergicneurodegeneration
NOX2在环境毒素诱导的多巴胺能神经变性中的作用和潜在机制
QingshanWang/王青山（DalianMedicalUniversity,大连医科大学）
Cholesterolmetabolismhomeostasisprogrammingmechanismandpotentialearlywarningmarkerofdexamethasoneinducedhippocampalsynapticinjuryinoffspring
地塞米松致后代海马突触损伤的胆固醇代谢稳态程序化机制及潜在预警标志物
DanXu/徐丹（SchoolofBasicMedicalSciences,WuhanUniversity,武汉大学基础医学院）
Studyonplacentalpathogenesisforabnormalfetaldevelopmentcausedbyenvironmentalcadmiumexposureduringpregnancy
孕期环境镉暴露致胎儿发育异常的胎盘发病机制研究
HuaWang/王华（AnhuiMedicalUniversity,安徽医科大学）
Integrativeeffectsbasedonbehavior,physiologyandgeneexpressionoftritiatedwateronzebrafish
基于氚水对斑马鱼行为、生理和基因表达的综合影响
FenmeiCui/崔凤梅（InstituteofRadiologicalMedicineandProtection,SoochowUniversity,苏州大学放射医学与防护研究所）
Prenatalpolycyclicaromatichydrocarbonsexposureandneurodevelpmentalretardation:cohortandmechanismstudy
产前多环芳烃暴露和神经发育迟缓：队列和机制研究
JishengNie/聂继盛（ShanxiMedicalUniversity,山西医科大学）
17:10-17:30
RNAm6AepitranscriptomerevealsthetoxicologicalmechanismsofmetaloxidenanoparticlesRNAm6A表观转录组揭示金属氧化物纳米粒子的毒理学机制
ChengyongHe/何承勇（XiamenUniversity,厦门大学）
YT-3:MechanisticToxicology(2)机制毒理学-2Chairs主席:GeyuLiang/梁戈玉，YanlingMou/牟艳玲
08:00-08:25
ThemechanismofNLRP3inflammasome-mediatedneuroinflammationinspecialenvironmentalfactorsinducedneurologicalimpairment
NLRP3炎症小体介导的神经炎症在特殊环境因素诱发神经功能损害中的作用机制
DiyaWang/王迪雅(FourthMilitaryMedicalUniversity,第四军医大学)
08:25-08:50
EvaluationofEfficacyandSafetyofCOVID-19VaccineBasedonRhesusMonkeyModel
基于恒河猴模型的新冠疫苗有效性和安全性评价
YichaoTian/田义超（HubeiTopgeneBiotechnologyCo.,Ltd.,湖北天勤生物科技有限公司）
08:50-09:15
AntifungalagentTerbinafinerestrainstumorgrowthinpreclinicalmodelsofhepatocellularcarcinomaviaAMPK-mTORaxis
抗真菌药物特比奈芬通过AMPK-mTORaxis抑制肝癌生长
XiaoyanYuan/苑晓燕（Bayer-BayerCropScience(China)Co.,Ltd.,拜耳作物科学（中国）有限公司）
09:15-09:40
ElucidatethepotentialmechanismofEucommiaeCortexagainstosteoporosisbynetworkpharmacology
网络药理学阐明杜仲抗骨质疏松的潜在机制
YunLiu/刘韵(GuangdongInstituteofBiologicalProductsandPharmaceuticals,广东省生物制品与药物研究所)
09:40-10:00
Bacterialwhole-cellbiosensorsforvisualmonitoringoftoxicheavymetalsintheenvironment用于视觉监测环境中有毒重金属的细菌全细胞生物传感器
ChangyeHui/惠长野(ShenzhenOccupationalDiseasePreventionandTreatmentInstitute,深圳市职业病防治院)
10:00-10:20
YT-4:NewTechnologyandModelofToxicology毒理学新技术与模型Chairs主席:ZhidongWang/王治东，XinyuanZhao/赵新元
10:20-10:40
ResearchprogressofcarcinogenicitymodelKI.C57-RASV2.0致癌性模型KI.C57-RASV2.0的研究进展
ChangfaFan/范昌发（ChinaInstituteofFoodandDrugControl,中国食品药品检定研究院）
10:40-11:00
Theneurotoxicityandunderlyingmechanismsofantimony锑的神经毒性和潜在机制
XinyuanZhao/赵新元（NantongUniversitySchoolofPublicHealth,南通大学公共卫生学院）
11:00-11:20
Screeningofadministrationconditionsforinhalationstudy吸入研究给药条件的筛选
YanlingMou/牟艳玲（DrugSafetyEvaluationCenter,ShandongAcademyofMedicalSciences,山东省医学科学院药物安全评价中心）
11:20-11:40
Establishmentofaninvitromethodofrabbitembryotoxicitywithtoxicokineticsstudy兔胚胎毒性体外毒代动力学研究方法的建立
JunGuo/郭隽（ShanghaiInstituteforBiomedicalandPharmaceuticalTechnologies.,上海市生物医药技术研究院）
YT-5:AppliedToxicology应用毒理学
Chairs主席:QuanjunWang/王全军，JishengNie/聂继盛
13:30-14:00
Constructionofthelung-on-a-chipanditstoxicologicalapplication肺芯片的构建及其毒理学应用
GeyuLiang/梁戈玉（SoutheastUniversitySchoolofPublicHealth,东南大学公共卫生学院）
14:00-14:30
Preliminarystudyonthehazardidentificationofendocrinedisruptors内分泌干扰物危害识别的初步研究
QianBian/卞倩（JiangsuProvincialCenterforDiseaseControlandPrevention,江苏省疾病预防控制中心）
14:30-15:00
PostnatalexposuretotetrabromobisphenolAretardedtestisdevelopmentinmice小鼠出生后接触四溴双酚A延迟睾丸发育
YuanyuanLi/李圆圆（ChineseAcademyofSciences,中国科学院）
15:00-15:30
DifferentsensitivitiesofmammalianTRPV1receptorsandevaluationofstingevokedbysomealkanolamides
哺乳动物TRPV1受体的不同敏感性及对某些链烷醇酰胺引起的刺痛的评价
TianChen/陈田（ShanghaiCenterforDiseaseControlandPrevention.,上海市疾病预防控制中心）
GuofengHall/国风厅(On-site，线下)VeterinaryToxicologyForum，兽医毒理学论坛
OpeningArrangeofVeterinaryToxicology兽医毒理会前会
CongmingWu,吴聪明(ChinaAgriculturalUniversity,中国农业大学）
VT-1:InvitedSpeakers特邀报告Chair主席:XumingDeng/邓旭明
Safetyevaluationandrequirementsinthereviewofnewveterinarydrugs新兽药审评中的安全性评价要求
XiaWang/汪霞(ChinaInstituteofVeterinaryDrugsControl,中检所兽药审评处)
Molecularecotoxicologyandriskassessmentofveterinarydrugs/additives兽药/添加剂的分子生态毒理学及风险评估
YongxueSun/孙永学(SouthChinaAgriculturalUniversity,华南农业大学)
15:00-15:20
InvitedSpeakers特邀报告Chair主席:ShijinBu,卜仕金
15:20-15:50
Animalfoodsnon-targetedscreeningofchemicalhazards动物性食品中化学危害物的非靶向筛查
BingShao/邵兵（BeijingCDC,北京预防疾病控制中心）
15:50-16:20
Protectivemechanismof7-hydroxycoumarinandmettl3/m6A/mirna-873-5poncolistininducednephrotoxicity
7-羟基香豆素及METTL3/m6A/miRNA-873-5p对黏菌素所致肾毒性的保护机制研究
JianyongLi/李继昌（NortheastAgriculturalUniversity,东北农业大学）
16:20-17:30
VT-2:Professionalcommitteegeneralelection,专业委员会换届选举
VT-3:ClinicalVeterinaryToxicology，临床兽医毒理学Chair主席:XiuyingZhang,张秀英
08:00-08:20
ThemolecularmechanismoferythroiddifferentiationaffectedbyT-2toxinonK562cellsT-2毒素影响K562细胞向红系细胞分化的分子机理研究
XuWang/王旭（HuazhongAgriculturalUniversity,华中农业大学）
08:20-08:40
Aspirineugenolesterimprovesparaquatinducedoxidativedamagebymitochondrialapoptosis阿司匹林丁香酚酯通过线粒体凋亡途径改善百草枯诱导的氧化损伤
JianyongLi/李剑勇（LanzhouInstituteofHusbandryandPharmaceuticalSciencesofCAAS,中国农科院兰州牧药所）
08:40-09:00
MechanismofdruginteractionmediatedbyABCtransporterhighlyexpressedinchickenintestinaltract,鸡肠道高表达的ABC转运蛋白介导药物间相互作用的机制
LipingWang/王丽萍（NanjingAgriculturalUniversity,南京农业大学）
09:00-09:20
Molecularmechanismandtargetedinterventionofpolymyxinnephrotoxicity多黏菌素肾毒性分子机制及靶向干预研究
ChongshanDai/代重山（ChinaAgriculturalUniversity,中国农业大学）
09:20-09:40
ResearchontoxictraditionalChinesemedicinesandattenuatedandsynergisticeffects有毒中药及减毒增效研究
ZhihuiHao/郝智慧（ChinaAgriculturalUniversity,中国农业大学）
VT-4:BasicVeterinaryToxicology，基础兽医毒理学Chair主席:BingShao,邵兵
10:00-10:15
NationalVeterinaryDrugSafetyEvaluationCenter,国家兽药安全评价中心
10:15-10:30
SouthChinaAgriculturalUniversity,华南农业大学
10:30-10:45
SichuanAgriculturalUniversity,四川农业大学
10:45-11:00
HuazhongAgriculturalUniversity,华中农业大学
11:00-11:15
UnitedNationsQualityDetectionGroupCo.,Ltd,西安国联质量检测技术股份有限公司
11:15-11:30
TianjinBohaiAgricultureandAnimalHusbandryUnitedIndustryResearchInstituteCo.,Ltd,天津渤海农牧联合产业研究院有限公司
11:30-11:45
LanzhouInstituteofHusbandryandPharmaceuticalSciencesofCAAS,中国农科院兰州牧药所
VT-5:VeterinaryToxicology,YoungScholarForum,兽医毒理学青年论坛Chair主席:JianyongLi/李剑勇
Aproposed“steric-likeeffect”fortheslowdownofenrofloxacinantibioticmetabolismbyciprofloxacin,anditsmechanism；环丙沙星减慢恩诺沙星抗生素代谢的“类位阻效应”的提出及其作用机制
XaoqingXu/徐小庆(HuazhongAgriculturalUniversity,华中农业大学)
13:40-13:50
Effectsofflorfenicolcombinedwithcopperonbiofilmformationandnitrogenregulatorygeneexpressioninrhizobia;氟苯尼考联合铜对根瘤菌生物膜形成及氮调控基因表达的影响
MeiWang/王美(SouthChinaAgriculturalUniversity,华南农业大学)
13:50-14:00
InvestigationoftheuptakeandtransportofaspirineugenolesterinCaco-2cellsmodel;阿司匹林丁香酚酯在Caco-2细胞模型中的摄取和转运研究
QiTao/陶琦(LanzhouInstituteofHusbandryandPharmaceuticalSciencesofCAAS,中国农科院兰州牧药所)
14:00-14:10
TheVEGFR2/mTOR/S6K1SignalPathwayInTheAngiogenesisPromotionInducedByRoxarsone.VEGFR2/mTOR/S6K1通路在洛克沙胂促血管生成中的作用
MengZhang/张蒙(YangzhouUniversity,扬州大学)
14:10-14:20
Discoveryandmechanismofmethuosis,anovelcelldeath,mediatesmaduramicin-inducedcardiotoxicity
一种新型细胞死亡methuosis介导马度米星铵致心脏毒性的发现与机制
XiugeGao/高修歌(NanjingAgriculturalUniversity,南京农业大学)
14:20-14:30
NovelTet(L)effluxpumpvariantsconferringresistancetotigecyclineanderavacyclineinStaphylococcusspp.葡萄球菌替加环素和依拉环素耐药新型Tet(L)变异体的鉴定及功能分析NannanWang/王囡囡(HenanAgriculturalUniversity，河南农业大学)
14:30-14:40
AristolochicAcidA-inducedhepatotoxicityinTianfubroilersrelatestooxidativestress-mediatedapoptosisandmitochondrialdamage
马兜铃酸A诱导的天府肉鸡肝毒性与氧化应激介导的细胞凋亡和线粒体损伤有关
DanXu/徐丹(SichuanAgriculturalUniversity,四川农业大学)
14:40-14:50
ChenGao/高琛(ChinaAgriculturalUniversity,中国农业大学)
14:50-15:00
IvermectininducesBCRP/ABCG2expressionandfunctionbyregulationofCXRandmRNAstabilityinchickenprimaryhepatocytes
伊维菌素通过调节CXR和mRNA稳定性诱导鸡原代肝细胞中BCRP/ABCG2的表达和功能
YujuanZhang/张瑜娟(JiangsuUniversityofScienceandTechnology,江苏科技大学)
15:00-15:10
Genderdifferencesinmetabolismandbloodcoagulationamongratsafterafungicidesodiumdehydroacetateexposure杀菌剂脱氢乙酸钠暴露后大鼠代谢和凝血的性别差异
XinChen/陈新(YangzhouUniversity,扬州大学)
15:10-15:20
Mobilizationoftet(X4)byIS1familyelementsinporcineEscherichiacoliisolates.猪源大肠杆菌中IS1家族元件介导tet(X4)基因转移的研究
RunhaoYu/于润浩(HenanAgriculturalUniversity，河南农业大学)
MyricetinattenuatesSalmonellamediatedcytotoxicitybytargetingT3SS杨梅素靶向III型分泌系统抑制沙门氏菌介导的细胞毒性作用
JianfengWang/王建锋(JilinUniversity,吉林大学)
Aconitineinducescellapoptosisviamitochondriaanddeathreceptorsignalingpathwaysinhippocampuscellline
乌头碱通过线粒体和死亡受体信号通路诱导海马细胞凋亡
HuiWang/王辉(NorthwestA&FUniversity,西北农林科技大学)
15:40-15:50
Newtricksofolddrugs:Repurposingananticoccidialagenthalofuginoneforcancertherapy，老药新用：将抗球虫药常山酮用于癌症治疗
DaweiGuo/郭大伟(NanjingAgriculturalUniversity,南京农业大学)
15:50-16:00
T-2toxininducesmitochondrialdysfunction,G1-phasearrest,andautophagyinPC12cellsviatheactivationofROS/JNKpathways
T-2毒素通过激活ROS/JNK途径诱导PC12细胞线粒体功能障碍、G1期阻滞和自噬
TunSun/孙暾(ChinaAgriculturalUniversity,中国农业大学)
16:00-16:20
VT-6:SummaryofVeterinaryToxicology,兽医毒理学论坛总结
YuqingHall/玉清厅(On-site，线下)
呼吸毒理学论坛，RespiratoryToxicologyForum
管理毒理与风险评估论坛,RegulatoryToxicologyandRiskAssessment
RT-1:InvitedSpeakers特邀报告Chair主席:ZhiweiSun/孙志伟
EpidemiologyandpreventivemeasuresofCOVID-19inWuhan武汉新冠肺炎的流行病学与预防对策
TangchunWu/邬堂春（HuazhongUniversityofScience&Technology,华中科技大学）
Tobaccohazardsandsmokingcessation烟草危害及戒烟
DanXiao/肖丹（China-JapanFriendshipHospital,中日友好医院）
Reviewofresearchontheimpactsofatmosphericpollutiononthelungcancer大气污染对肺癌的的影响
RongshouZheng/郑荣寿（CancerHospitalChineseAcademyofMedicalSciences,中国医学科学院肿瘤医院）
AssociationoffineparticulatematterairpollutionanditsconstituentswithlungfunctionPM2.5及其组分对慢阻肺患者肺功能的影响
TingYang/杨汀（China-JapanFriendshipHospital,中日友好医院）
RT-2:ToxicologyofAirPollutants空气污染物毒理Chair主席:RuiChen/陈瑞
XiaohuaLiu/刘晓华（BeijingInstituteofPharmacologyandToxicology,北京药物研究所）
ExposuretoindoorPM2.5andphthalicacidestersandrespiratoryresponsesinhealthyyoungadults:Arandomized,crossovertrialofairpurification
室内空气中细颗粒物及邻苯二甲酸酯暴露对年轻健康成人的呼吸健康效应
ResearchonanewmodelofCOPDbasedonthemechanismofautoimmunity基于自免疫机制的新型慢阻肺模型研究
ZhihuaChen/陈志华（SecondAffiliatedHospitalofZhejiangUniversitySchoolofMedicine,浙江大学医学院附属第二医院）
ToxiceffectsofPM2.5exposureonadiposetissuesPM2.5暴露的脂肪毒性作用
CuiqingLiu/刘翠清（ZhejiangChineseMedicalUniversity,浙江中医药大学）
ExposuretoambientPM2.5andlungfunctioninchildren,PM2.5暴露对儿童肺功能的影响
RT-3:MolecularMechanismofRespiratoryToxicology呼吸毒理分子机制Chair主席:TingYang/杨汀
Pathogenicmechanismofairpollutiononchronicobstructivepulmonarydisease,大气污染对慢阻肺影响的机制研究
FenLan/兰芬（SecondAffiliatedHospitalofZhejiangUniversitySchoolofMedicine,浙江大学医学院附属第二医院）
FeifeiFeng/冯斐斐(DepartmentofToxicology,CollegeofPublicHealthofZhengzhouUniversity,郑州大学公共卫生学院卫生毒理学教研室)
Alpha-lipoicacidattenuatessilica-inducedpulmonaryfibrosisbyregulatingoxidativestressandenergyhomeostasisinmice
α-硫辛酸调节小鼠氧化应激及能量稳态抗矽肺纤维化
YingzhengZhao/赵英政(XinxiangMedicalUniversity,新乡医学院)
Transcriptomic-basedstudyofratsilicosismodel基于转录组学的大鼠矽肺模型研究
JiaqiLv,BinLi/吕佳琦，李斌(NationalInstituteforOccupationalHealthandPoisonControl,CDC,中国疾病预防控制中心职业卫生与中毒控制所)
Theroleandmolecularmechanismofm6Amodificationinpulmonaryfibrosisdevelopmentinducedbyatmosphericparticulatematter
m6A修饰在大气细颗粒物致肺纤维化中的作用及分子机制
RongZhang/张荣(HebeiMedicalUniversity,河北医科大学)
RT-4:InhalationToxicityandSafety呼吸毒性安全性评价Chair主席：ShaoxiCai/蔡绍熙
Researchanddevelopmentofdrugevaluationandactionmechanismbasedonpulmonaryfunctionprotection
基于肺功能保护的药物评价研发及作用机制探索
HongtaoJin/靳洪涛（中国医学科学院北京协和医学院新药安全评价研究中心，NewDrugSafetyEvaluationCenterinChineseAcademyofMedicalSciences&PekingUnionMedicalCollege)
Qualitycontrolofinhaledpreparationsinnon-clinicalstudies吸入制剂非临床研究中的质量控制
XuewuLiu/刘学武（HunanPrimaDrugResearchCenterCo.,Ltd.湖南普瑞玛药物研究中心有限公司）
Thegeneralconsiderationsinnon-clinicalevaluationofinhalationalformulations吸入制剂临床前评价的一般考虑
JinCao/曹瑾（JoinnLaboratories（Suzhou）Inc.昭衍（苏州）新药研究中心有限公司）
Designstrategiesandcasesofinhalationtoxicitytestsforpesticidesandchemicals农药和化学品吸入毒性试验设计策略和案例
ZongchengWu/吴宗澄（NationalShenyangNewDrugSafetyEvaluationandResearchCenter.国家沈阳新药安全评价研究中心）
RTRA:RegulatoryToxicologyandRiskAssessment,管理毒理与风险评估论坛Chairs:QingshengZhang/张庆生,ShuxiaXing/邢书霞
Interpretationfortechnicalguidanceforcosmeticssafetyassessment
《化妆品安全评估技术导则》解读
XinrongPei/裴新荣(NationalInstitutesforFoodandDrugControl,中国食品药品检定研究院)
Riskassessmentanditsapplicationfromtheperspectiveofindustry行业视角下的风险评估及其应用
TingtingZhu/朱婷婷(Procter&GambleBeijingInnovationCenter,北京宝洁技术有限公司)
Overviewofcontrolstrategiesforgenotoxicimpuritiesinpharmaceuticalchemicals化学药品中遗传毒性杂质的控制策略
HuaChen/陈华(NationalInstitutesforFoodandDrugControl,中国食品药品检定研究院)
Riskassessmentoftracechemicalsinconsumerproducts消费品中痕量物质的风险评估
HaixiaSui/隋海霞（ChinaNationalCenterforFoodSafetyRiskAssessment,国家食品安全风险评估中心)
Post-marketsurveillanceofconsumerproducts消费品安全风险监测
YueZhao/PeiWang/赵越/王沛(Procter&Gamble(Guangzhou),广州宝洁有限公司)
16:20-16:50
Toxicologicalassessmentofpesticidesmetabolites:groupingandread-across农药代谢物毒性评价：分组与交叉参照
Xiaoyan,Yuan/苑晓燕,AnjaHueser(BayerAG,拜耳股份公司)
YixiangHall/溢香居(On-site，线下)
ZhejiangSocietyofToxicologyForum，浙江省毒理学会论坛
OpeningSpeechbyPresidentofZhejiangSocietyofToxicologyChair:FanzhuLi/李范珠,QingweiZhao/赵青威
ZT-1:InvitedSpeakers特邀报告
Chairs:XingguoZhang/张幸国,WeiYang/杨巍,ZhiyuChen/陈致宇
09:00-09:40
Inheritingtheessence,stickingtotherightpathandmakinginnovations:thehighqualitydevelopmentofChinesemedicineandHealthyChina
传承精华，守正创新：中医药高质量发展与健康中国
YongshengFan/范永升（ZhejiangChineseMedicalUniversity,浙江中医药大学）
09:40-10:20
Realworldstudyon2019-nCoVvaccine新冠灭活疫苗真实世界研究
YuanshengHu/胡苑笙（SinovacBiotechCo.,Ltd.北京科兴生物制品有限公司）
10:20-10:30
10:30-11:10
Dataminingofadversedrugreactionsandclinicalapplication药物不良反应挖掘与临床应用
QingweiZhao/赵青威（TheFirstAffiliatedHospital,ZhejiangUniversitySchoolofMedicine,浙江大学医学院附属第一医院）
ZT-2:主题沙龙（一）RoundTableDiscussion
MOOChelpstoreformthemodeoftoxicologyteaching,慕课助力毒理学教学模式改革Chair:DajingXia/夏大静
11:10-12:00
特邀嘉宾：
1.PeilinYu/余沛霖(ZhejiangUniversity,SchoolofPublicHealth,浙江大学公共卫生学院)2.CuiqingLiu/刘翠清(ZhejiangChineseMedicalUniversity浙江中医药大学)
3.JinXu/徐进(NingboUniversity,宁波大学)
4.ZhenLi/李真(NingboUniversity宁波大学)
ZT-3:ToxicologyScholarForum,毒理学者论坛
Chairs:HonggangLou/楼洪刚,GuojunJiang/蒋国军,JunYang/杨军
13:30-14:10
Safetyevaluationandtoxicokineticstudyofbenzothiaxanthonederivatives苯并硫杂蒽类衍生物S3的安全性评价及毒代动力学研究
YanlingWu/吴艳玲（ZhejiangProvincialCenterforDiseaseControlandPrevention,浙江省疾病控制预防中心)
14:10-14:40
Ambientfineparticulatematteroncirculatingendothelialprogenitorcells:sexmatters大气细颗粒物对循环内皮前体细胞的性别差异化影响，
QinghuaSun/孙庆华（ZhejiangChineseMedicalUniveristy,浙江中医药大学)
14:40-15:20
Toxiceffectsandmolecularmechanismsofnanoparticles纳米颗粒物的毒效应及分子机制研究
PeilinYu/余沛霖（ZhejiangUniversity,SchoolofPublicHealth,浙江大学公共卫生学院)
ZT-4:YoungScholarForum,青年论坛
Chairs:XiaopingChen/陈晓萍,YuanqiangLu/陆远强
Validation,Optimization,andApplicationoftheZebrafishDevelopmentalToxicityAssayforPharmaceuticalsUndertheICHS5(R3)Guideline
依照ICHS5(R3)原则建立斑马鱼发育毒性测试模型及其应用
YongZhang,张勇(HangzhouHunterBiotechnology，Inc.杭州环特生物)
Multi-omicprofilingrevealthemixturetoxicityofdifenoconazoleandtebuconazoleinlarvalandadultzebrafish
多组学分析揭示苯醚甲环唑和戊唑醇对斑马鱼幼鱼和成鱼联合毒性效应
JinhuaJiang,蒋金花(ZhejiangAcademyofAgriculturalSciences,浙江省农业科学院)
Machinelearningapproachtopredictantibioticresistancegeneswithlowsequenceconservation低保守度细菌耐药基因的机器学习预测模型
KunkaiSu,苏锟楷(1stAffiliatedHospital,ZhejiangUniversity,浙江大学医学院附属第一医院)
16:00-16:10
CancerHazardIdentificationandExposureAssessmentofPerfluorodecanoicAcid全氟癸酸的癌症危害识别和暴露评估
ZhenyaChen,陈振亚(ProyaCosmeticsCo.,Ltd.,珀莱雅化妆品股份有限公司)
16:10-16:20
Theconstructionof“arsenicprodrug”loadedmultifunctionaldrugdeliverysystemanditsinsituactivationforthesynergistictherapyoflivercancer
“砷前药”负载多功能给药系统的构建及其在肝癌协同治疗中的原位激活
YueZhang,张悦(ZhejiangChineseMedicalUniveristy,浙江中医药大学)
16:20-16:30
Expertcomment,专家点评
主题沙龙（二）RoundTableDiscussion创新中药制剂研发与安全性评价
Research,DevelopmentandSafetyEvaluationonInnovativeDrugofTraditionalChineseMedicine
Chair:GaoliZheng/郑高利
16:30-17:20
1.ChenpingWen/温成平(ZhejiangChineseMedicalUniversity浙江中医药大学)
2.BilianChen/陈碧莲(ZhejiangInstituteofFoodandDrugInspection浙江省食品药品检验研究院)
3.GangCao/曹岗(ZhejiangChineseMedicalUniversity浙江中医药大学)
4.GaoliZheng/郑高利(HangzhouMedicalCollege杭州医学院)
5.JiangningHu/胡江宁(ZhejiangConbaPharmaceuticalCo.,Ltd.浙江康恩贝制药有限公司)
17:20-17:30
Discussionandconclusion.会议讨论总结Chair:XingguoZhang/张幸国